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Metabolism answers the two questions most frequently posed by medical students: What do I need to know? and What is the significance of this information? The author integrates multidisciplinary concepts into a concise format, emphasizing basic principles, function, and regulation without digressing into discussion about many metabolic intermediates and tedious structural details. Clinical examples are used frequently to emphasize the connection between disease and abnormalities in metabolism.
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Table of Contents
- DEDICATION
- PREFACE
- ACKNOWLEDGMENTS
- 1 THE CELL: THE FUNDAMENTAL UNIT OF METABOLISM
- 2 PROTEINS: THE WORKHORSES OF THE BODY
- 3 ENZYMES: THE CATALYTIC AGENTS OF METABOLISM
- 4 OXYGEN TRANSPORT AND STORAGE: HEMOGLOBIN AND MYOGLOBIN
- 5 NUTRITION AND METABOLISM
- 6 BIOENERGETICS: BASIC PRINCIPLES OF ENERGY METABOLISM
- 7 PRINCIPLES AND DESIGN OF METABOLISM
- 8 REGULATION OF METABOLISM
- 9 OVERVIEW OF CARBO-HYDRATE METABOLISM: THE IMPORTANCE OF REGULATING BLOOD GLUCOSE LEVELS
- 10 DIGESTION AND ABSORPTION OF CARBOHYDRATES
- 11 GLYCOLYSIS: THE CENTRAL PATHWAY OF GLUCOSE DEGRADATION
- 12 GLYCOGEN METABOLISM: STORAGE AND MOBILIZATION OF GLUCOSE
- 13 GLUCONEOGENESIS: THE DE NOVO SYNTHESIS OF GLUCOSE AND ITS ROLE IN PREVENTING HYPOGLYCEMIA
- 14 PENTOSE PHOSPHATE PATHWAY: GENERATION OF NADPH AND PENTOSES
- 15 INTERCONVERSION OF MONOSACCHARIDES: GALACTOSE, FRUCTOSE, GLUCURONIC ACID, AND AMINO SUGARS
- 16 GLYCOPROTEINS AND PROTEOGLYCANS
- 17 CONNECTIONS BETWEEN METABOLIC PATHWAYS
- 18 INTRODUCTION TO LIPID METABOLISM: DIGESTION AND ABSORPTION OF DIETARY FAT
- 19 LIPID TRANSPORT: LIPOPROTEIN STRUCTURE, FUNCTION, AND METABOLISM
- 20 FATTY ACID METABOLISM
- 21 CHOLESTEROL AND STEROL METABOLISM
- 22 COMPLEX LIPIDS: PHOSPHOLIPIDS, SPHINGOLIPIDS, AND EICOSANOIDS
- 23 PATHWAYS OF LIPID METABOLISM: SUMMARY, REGULATION, AND COORDINATION
- 24 INTRODUCTION TO AMINO ACID METABOLISM: DIGESTION AND ABSORPTION OF DIETARY PROTEIN
- 25 AMINO ACID CATABOLISM: DISPOSAL OF NITROGEN AND CARBON SKELETONS
- 26 ONE-CARBON METABOLISM AND THE SYNTHESIS OF NONESSENTIAL AMINO ACIDS
- 27 SPECIALIZED PRODUCTS DERIVED FROM AMINO ACIDS
- 28 NUCLEOTIDE METABOLISM
- Index
